CRISMO (Clinical Research Investigator Site Management Organization) is a South African-based

organization that specializes in managing and conducting clinical trials. Our aim is to advance

healthcare research through ethical, high-quality, and community-relevant studies in collaboration

with our partners.

We specialize in conducting clinical research across various therapeutic areas, including infectious
diseases, maternal and paediatric health, vaccine development, diagnostic studies, and other related
fields. Our expertise also includes behavioural and social science studies, along with multipurpose
technology research.

Yes, all our studies adhere to stringent ethical and regulatory standards. They are reviewed and
approved by the South African Health Products Regulatory Authority (SAHPRA) and independent
ethics committees. Continuous monitoring by regulatory bodies ensures participant safety and
compliance.

Interested individuals can contact our recruitment team by submitting their details (name, age, contact
information, and any relevant health information) to info@crismo.co.za. Our team will screen and
guide you through the enrolment process if you meet the eligibility criteria.

After submitting your details, our recruitment team will review your information against the study’s
specific requirements. If you qualify, you will be contacted for further screening and informed consent
procedures.

Participants are required to:
• Provide informed consent after understanding the study process.
• Commit to the schedule of study visits and procedures.
• Communicate openly with site staff and report any side effects or health issues promptly.
• Uphold honesty and integrity throughout the study duration.

Study visits are scheduled appointments at our research site to conduct procedures outlined in the
study protocol. These visits may involve physical exams, blood tests, administration of medication, or
other necessary data collection. Visits are essential to ensure the study’s success and participant safety.

Participants are reimbursed for their time and transportation costs. Reimbursement amounts are pre-
approved by an independent committee and vary depending on the study.

All side effects or symptoms must be reported to the site staff immediately. Our investigators will
assess the situation, provide necessary care, and determine if the side effects are related to the study
product.

CRISMO is a research organization focused on conducting clinical trials based on specific research
protocols. Unlike clinics, we do not provide general medical care to the public.

We provide these services only when they are part of a study protocol. For general public services,
we encourage individuals to visit healthcare facilities or clinics.

Blood samples are used for laboratory testing as per the study protocol. If storage for future research
is required, participants’ consent will be obtained beforehand.

If you feel unwell during the study, notify our site staff immediately. The study investigator will assess
your condition and determine the appropriate course of action, which may include referrals or
adjustments to your participation.

The length of study visits varies depending on the procedures involved. We recommend setting aside
sufficient time, as some visits may take longer than others.

Yes, study results are shared with participants upon completion of the study. Our team will ensure
results are disseminated to those who completed their scheduled visits.

Yes, CRISMO is always open to collaborating with qualified investigators. Please contact us at Tel:
+27 11 038 6814 / Email: info@crismo.co.za with your credentials and interest.

Organizations interested in partnering with us for clinical trials can contact our Business Development
team at info@crismo.co.za.

Visit our website or contact our team to stay updated on available and upcoming clinical trials. You
can also subscribe to our newsletter for the latest news.

Our research sites are located in multiple regions across South Africa. CRISMO Research Centre is
located at Bertha Gxowa Hospital, Villa Heidi Building, Ground Floor, Cnr Joubert and Hospital Street,
Germiston, Gauteng, South Africa, 1401. CRISMO Bloemfontein Research Centre is located Netcare
Universitas Private Hospital, 1 Logeman Street, Suite F02 First Floor, Bloemfontein Free State, South
Africa, 9301.

CRISMO stands out as a research site due to its community-focused approach and commitment to
capacity building within public health facilities.